Bacopa monnieri (Brahmi)

What is Bacopa monnieri?

Bacopa monnieri is a traditional Ayurvedic (Indian) medicinal herb which helps to support memory and learning.

The history of Bacopa monnieri use

Bacopa monnieri, also known as bacopa and brahmi, has a very long history of traditional use. It was cited in the religious, social and medical literature of India as long ago as around 1500 BC.

Bacopa monnieri can also be traced back to the time of Athar Ved (C.800 BC), where it was mentioned in the the third chapter of Athar Samhita). It later found a place in the compilation of teachings of the ancient Persian prophet Zoroaster (the founder of the Zorastrian religion), (c. 600 BC).

More recently, the government of India has recognised the benefits of Bacopa monnieri by releasing a postal stamp featuring the herb.

In its many mentions throughout history, Bacopa monnieri has been associated with a variety of health benefits - yet it’s the memory and learning effects that have attracted the most attention in the last few decades.

The specific extract used by Flordis

The specific Bacopa monnieri extract used by Flordis is known as CDRI 08. CDRI 08 is extracted and formulated using a special process. This individual and highly technical process ensures a consistent form and amount of Bacopa monnieri is used in every formulation - meaning each final product will contain the same high quality extract.

Natural medicines can vary considerably depending on how they are produced. Flordis believes it’s the science behind growing, harvesting and processing that delivers the true health benefits of natural medicine. That’s why in the making of a Flordis medicine, careful attention is applied to plant species and growing methods through to cultivation and harvest, using precise processes to help produce consistent crops. This is continued with extracting and manufacturing of specific ingredients following a series of strict controls to help deliver a consistent medicine from one batch to the next.

It is this specific medicine that is tested in clinical trials. And it’s the same medicine that you receive, which is one of the reasons you can feel good about its effectiveness.Flordis medicines follow processes where all of the steps involved in the growth and manufacture of the natural medicine are tightly controlled to reduce variability and to help ensure consistency.

The specific Bacopa monnieri extract used by Flordis is known as CDRI 08. CDRI 08 is extracted and formulated using a special process. This individual and highly technical process ensures a consistent form and amount of Bacopa monnieri is used in every formulation - meaning each final product will contain the same high quality extract.

The seed to patient journey

  • The specific species of herb is selected
  • Standardised cultivation and harvesting occurs (helping to ensure a consistent phytochemical profile) - followed by harvesting, drying and processing.
  • A series of strict controls are applied to the manufacturing processes - including everything from solvents and extraction methods through to packaging, storage and transportation of the final product - helping to ensure that every single product is consistent (we refer to this as “batch to batch consistency”)
  • Research and clinical studies are conducted on the finished product to validate its tolerability and efficacy

How it works

Researchers are still investigating exactly how Bacopa monnieri supports cognition and learning. The herb’s properties are thought to be multiple and complex. 1,2,3,4 The available scientific evidence indicates that Bacopa monnieri is an effective and well tolerated herbal nootropic (a cognitive aid) with benefits for memory attention and learning retention.

Also, due to its possible neuroprotective and antioxidant properties, Bacopa monnieri extract CDRI 08may play a role in helping to both benefit and protect certain cognitive functions. Some research indicates that Bacopa monnieri extract CDRI 08 can have a calming effect - meaning it can potentially be useful at times when your mental performance and mental clarity are compromised by feelings of stress and anxiety.5

Key studies on CDRI08

KeenMind contains the specific CDRI 08 extract which has more than 40 years of research supporting its benefits*, conducted by the Central Drug Research Institute (CDRI) in India.

KeenMind was first researched in 1974 and is still the subject of ongoing research.

Results from clinical trials have suggested that CDRI 08 may:

  • Help maintain healthy cognitive function
  • Support mental clarity
  • Help improve working memory
  • Assist in learning retention
  • Assist with concentration/ focus/ keeping to tasks / attention span
  • Be beneficial during times of stress/mild anxiety

Most recently, studies have been conducted at The Centre for Human Psychopharmacology at Swinburne University in Australia.5,6 In this research, CDRI 08 was linked with a positive effect on learning retention, memory and attention measures - with one double blind, placebo-controlled trial of 46 healthy adults finding that the extract significantly improved speed of visual information processing, learning rate and memory consolidation. The results also revealed that CDRI 08 can be beneficial when you’re feeling stressed or mildly anxious. This study also showed short-term effects on stress and mood by decreasing anxiety after taking CDR1 08.

Another trial conducted by the same research team showed that CDRI 08 decreased forgetfulness in 76 healthy mature adults after 90 days of treatment.6

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References

1. Bhattacharya, S.K. et al. Phytotherapy Research 2000; 14.3: 174-179.  2. Rai, D. et al. Pharmacology, Biochemistry and Behaviour 2003; 75: 823-830. 3. Jyoti, A. & Sharma, D. NeuroToxicology 2006; 27: 451-457.  4. Dulcy CP, et al. J Ethnopharmacol 2011; 134:55-61.  5. Stough et al. Psychopharmacology (Berl.). 2001, 156(4):481-484. 6. Stough et al.Phytotherapy Res. 2008 122(12):1629-1634. 

*CDRI 08 was first researched in 1974 and is still the subject of ongoing research – Singh chapter