Supports liver health

Legalon supports liver regeneration by protecting liver cells from toxins

A healthy functioning liver is vital for good health, but many of us put our liver under stress due to overconsumption of alcohol and/or rich, fatty, and processed foods. This may lead to feelings of fatigue, sluggishness, nausea, and uncomfortable fullness.

Legalon can help protect and prevent damage to liver cells, and help relieve associated feelings of fatigue and tiredness.

Scientific research has indicated that Legalon may help to protect, detoxify and regenerate liver cells* by:

  • Having an antioxidant effect 2,3
  • Exhibiting an anti-inflammatory action2,4
  • Aiding the renewal of healthy liver cells2,4,5
  • Assisting normal healthy detoxification and elimination processes2,3

Legalon has been recommended for over 45 years, and may also help relieve mild gastrointestinal discomfort so you can feel the difference to your health.1

Where to buy

Buy online
Pharmacy Online - Legalon
Mr Vitamins - Legalon
Australia Vitamins - Legalon
Chemist Warehouse - Legalon
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What makes Legalon different?

Legalon contains a clinically researched extract of milk thistle (Silybum marianum) referred to as MZ 80. Exclusive to Legalon, MZ 80 has been shown in clinical trials to support liver health. When taking Legalon, you can be confident you are receiving a consistent natural medicine that has been tested in clinical trials.

Consistency is important as there can be great natural variation in the extract used in milk thistle products. Even if they appear to use the same active ingredients, they can differ due to the plant that is used, growing methods, harvesting processes and manufacturing methods. The outcomes of clinical studies for natural medicines may only apply to the product that has been examined in the clinical trials.

Legalon is a natural medicine designed to support healthy liver function. This benchmark Milk thistle formulation has been used medically for over 45 years worldwide. Legalon is scientifically researched to help protect liver cells against toxins and support regeneration of liver cells by providing antioxidant support when liver cells are detoxifying. Further research shows Legalon can help relieve fatigue and mild gastrointestinal symptoms such as nausea and uncomfortable fullness.

Learn more about Silybum marianum >




Product details


Legalon contains a specific extract of Silybum marianum (MZ 80), also known as Milk Thistle. This specific extract has demonstrated efficacy and tolerability in numerous clinical trials. Legalon is made in Germany using patented manufacturing processes. Learn more about Legalon and the specific extract of Silybum marianum (MZ 80).

Available sizes
60 capsules  


Directions for use

Recommended dosage and directions

Adults and children over 12: 1 capsule three times a day.

Once the desired therapeutic outcome is achieved, the dose may be reduced to 1 capsule twice daily for maintenance. Use for as long as liver support is needed.


Legalon capsules are well tolerated with no known drug interactions, however some evidence suggests that silybum marianum may interfere with metronidazole. Legalon has demonstrated in large-scale studies including one involving over 2,000 participants showing a very low incidence of side effects.1,6 Follow up tolerability data has shown that ongoing administration can be of continued benefit with patients taking Legalon for up to six years.7


Frequently asked questions

Is Legalon likely to have any side effects?

Legalon is generally well tolerated. In rare cases, a mild laxative action has been observed after taking Legalon. It is important to speak with a healthcare professional if you are concerned about possible side effects.

Does Legalon interact with any medications?

There are no known interactions between Legalon and other medications however some evidence suggests that Silybum marianum may interfere with metronidazole.  If you are concerned about taking Legalon with any prescription medications, it is important to speak with a healthcare professional.

Can Legalon be used during pregnancy or lactation?

Legalon is not recommended during pregnancy or lactation as there are no published studies to establish its safe use during pregnancy or while breastfeeding.

Does it matter if Legalon is taken before or after food?

Legalon can be taken on an empty stomach; this has the advantage of allowing the active agent, silymarin, to be more quickly absorbed into the body – therefore acting more rapidly and effectively. However, if you are experiencing any gastrointestinal problems, Legalon can be taken during or after meals.  

How does Legalon differ from other silymarin products?

Legalon is a clinically researched extract of milk thistle, referred to as MZ 80. This is exclusive to Legalon, and has been shown in clinical trials to support liver health. When taking Legalon, you can be confident you are receiving a consistent natural medicine that has been tested in clinical trials.

Is Legalon gluten free?

Legalon does not have any known gluten containing ingredients but is not tested to be 'gluten free.'

Does Legalon contain lactose?

No, Legalon does not contain lactose.

Will Legalon affect my ability to drive and use machines?

Legalon capsules have no known adverse effects in these situations.

Where can I find Legalon?

Legalon is available from naturopaths, herbalists, other natural health practitioners, selected health food stores and pharmacies. If you go to the Where to buy button above and follow the instructions, you will be able to find a list of practitioners, health food stores and pharmacies in your area that either stock Legalon or will know how to order Legalon. Even if your local pharmacy is not on the list, they will be able to order it in for you.

Does Legalon contain any allergens?

Legalon contains no added wheat, soy and preservatives.

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Clinically Proven Natural Medicine

Quality & Consistency

Quality & Consistency

Flordis applies pharmaceutical grade processes to the development of natural medicines. This commitment to rigorous processes and to sourcing the highest quality ingredients results in a portfolio of premium natural medicines.

Clinical Research

Clinical Research

The medicine you find in Flordis products is the specific medicine that has been used in clinical trials, which is one of the reasons you can feel confident about its effectiveness.



Driven by evidence and applying a quality-first approach to the development of our medicines, Australians enjoy the health benefits that millions have experienced worldwide.


* Helps to protect liver cells against toxins and support regeneration of liver cells. Aids normal healthy detoxification and elimination process es in the body. +Legalon may help fatigue due to a liver under stress.

1. Albrecht M et al Z Klin Med (1992) 47 (2): 87-92. 2. World Health Organisation, 2002, WHOmonographs on selected medicinal plants Volume 2,World Health Organization, Geneva, Switzerland. 3. Dehmlow C, et al. Hepatology. 1996;23:749-754. 4. Trappoliere M, et al. J. Hepatology. 2009; 50:1102-111.) 5. Velussi M, et al. J Hepatology. 1997; 26:871-879. 6. Saller R et al Drugs 2001; 61 (14): 2035-63 7. Ferenci et al. J Hepatology 1989; 9:105-113.