Soho Flordis International

Panax ginseng (Panax ginseng G115®)

Enhances immunity, supports energy, and physical endurance

Panax ginseng is used in Ginsana to support energy levels and physical endurance

Panax ginseng is a highly valued plant traditionally used in Chinese medicine and more recently has been researched as an extract to support energy levels and physical endurance.3

In Ginsana®, a specific standardised extract from the roots of Panax ginseng C.A. Meyer, called G115® is used. Ginsana with G115 has been researched for over 35 years to support energy and endurance.3

Discover more about the specific extract G115 used in Ginsana and the key studies that demonstrate its possible benefits.

Panax ginseng in history

Panax ginseng is a perennial shrub, native to north-eastern China, Korea and Russia.2 Different forms and species of ginseng have been commonly used as a remedy to support the body in times of increased demand and to promote wellbeing and vitality.

You may have heard of ‘ginseng’ before, but it’s important to know that not all ginseng is the same. Ginseng comprises a genus called ‘Panax. Several species of ginseng exist within this, e.g. Panax ginseng CA Meyer, Panax notoginseng and so on. All are ginseng but Panax ginseng CA Meyer in particular is the one with a considerable clinical research base demonstrating its medical use.3 

Panax ginseng was first recorded in Chinese medicine over 2000 years ago, and has reportedly been the subject of thousands of published books and scientific papers before the year 2000.2,3,17

The herb’s name comes from Panax meaning ‘cure all’ in Greek and ginseng from the Chinese (Mandarin) rén shn meaning ‘person ginseng’ because of the human like shape of the plant’s root.

Panax ginseng in history

The specific extract used by Flordis: G115

G115 is the specific extract of Panax ginseng used by Flordis in Ginsana. Its first mention in scientific literature goes back to 1960, and it has over 40+ years of research supporting its use.1-3

Extract G115 is produced from the roots of Panax ginseng C.A. Meyer. This is where many of the known active constituents lie, including the important group of active components called ‘ginsenosides’. G115 contains a consistent and standardised amount of ginsenosides - 4% to be exact.

It takes up to five years, and involves multiple steps for a Panax ginseng root to become the G115 extract used in Ginsana. This careful and controlled production process helps ensure that each batch consistently has an optimal concentration of active therapeutic components. This makes it possible to investigate the efficacy of G115 in clinical studies and scientific research.3

The beneficial effect of G115 is based on numerous clinical trials. Results from the research and clinical studies suggest that G115 can be used to help:

  • Support physical and mental endurance and performance4,8,9,11-12
  • Maintains physical endurance and stamina8-11,19
  • Support energy levels3,4,18
  • Shorten recovery time after periods of physical demand8-10
  • Maintain general well-being10
The specific extract used by Flordis: G115

Research on how G115 may work

G115 is considered to help the body adapt in times of stress, and increased demand, G115 helps to support the capability of the body to overcome adverse external and internal influences.

G115 may help to:

  • Support endurance – By helping to influence energy utilisation in the muscles 3,18
  • Support energy levels and energy production – By helping to increase oxygen and support energy metabolism11,19,21
  • Support mental and physical capacity – By acting on the central nervous system – to reduce stress, physical and mental tension4,18
  • Actively support the body during times of increased demand to help shorten recovery times from stress6,8

 

The exact mode of action of G115 is not fully understood, however preclinical studies suggest that G115 can help raise the general level of cellular activity and that it may be able to increase Adenosine Triphosphate (ATP), the molecule that provides energy to cells in the body.22

Research on how G115 may work

G115 in Ginsana: Clinical trials

Over 25 clinical studies, and over 1000 participants3, have been conducted using  G115 over the last 40 years. The table below highlights some key clinical studies conducted on G115 in the areas of immunity, energy and endurance support. A selection of these studies have been summarised in a review of G115 published in 2005.3

Rosenfeld et al., 1989 4

50 patients with energy concerns
studied over 56 days

Significant improvement

  • Concentration plus a range of factors including tiredness

Open, placebo controlled study.

Scaglione F, et al., 199623

227 adults
studied over 12 weeks

IMPROVEMENT

  • In the immune response in vivo in humans
  • Reduced incidence of illness compared to placebo

Randomised, double-blind placebo controlled study

Forgo 19817

120 healthy adults
studied over 12 weeks

POSITIVE INFLUENCE

  • Physical and mental function

Double-blind placebo controlled study.

Forgo 19818

20 top sportsmen
studied over weeks

IMPROVEMENT

  • Oxygen absorption resulting in a better physical performance and shorter recovery time.

Open, comparison study.

Always read the label. This medicine may not be right for you. Read the warnings before purchase. Follow the directions before use. If symptoms persist, talk to your health professional.

Flordis Difference

 

Medicines with naturally sourced active ingredients can vary considerably depending on the species of plant chosen, the way they are grown and harvested, and the extraction and production processes. So it’s essential to ensure the specific active ingredient in your product is the same as that researched in clinical trials.

In Ginsana, we take care to use the same specific extract (G115®) that's been proven in clinical studies to help support immunity, energy and endurance. That’s why you can be confident that Ginsana can offer the same benefits as demonstrated in the clinical trials.

Learn more about the importance of plant extracts.

Ginsana with Panax ginseng G115: A Summary

>40 years of research

Numerous preclinical and clinical studies investigating the beneficial effect Panax ginseng.1,3

>25 Clinical trials

Support the role of G115 in enhancing energy and endurance levels.3

Consistent quality

Through our rigorous processes, quality controls and extensive testing we help ensure that the G115 extract is the same as the medicine tested in clinical trials to help support energy, physical endurance, and performance.3

Used worldwide

To help support energy, endurance, and performance.

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Not only do the clinical studies on our products demonstrate real health outcomes, they demonstrate the results you can expect from the same products you see on shelf. It’s all part of our Source to Patient philosophy.

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References
  1. The extract G115 was researched in 1981 and is still the subject of ongoing clinical research.
  2. Blumenthal, M. et al. (2000), Herbal Medicine Expanded Commission E Monographs, p. 170. 
  3. Scaglione F et al. 2005 Evid Based Integrative Med 2(4); 195-206.
  4. Rosenfeld MS, et al., Sem Med 1989;173(9):148-154. Cited by:  Scaglione F et al., Evid Based Integrative Med 2005;2(4);195-206.
  5. Gianoli AC , Riebenfeld D. Cytobiol Rev 1984;8(3):177-186. Cited by:  Scaglione F et al., Evid Based Integrative Med 2005;2(4);195-206.
  6. Dörling E et al. 1980, Notab Med 10(5):241-246. Cited by:  Scaglione F et al., Evid Based Integrative Med 2005;2(4);195-206.
  7. Forgo I, Kirchdorfer AM. Aerztl Praxis 1981;33(44):1784-1786. Cited by:  Scaglione F et al., Evid Based Integrative Med 2005;2(4);195-206.  
  8. Forgo I et al. 1981, Med Welt 32(19):751-756. Cited by:  Scaglione F et al., Evid Based Integrative Med 2005;2(4);195-206.  
  9. Forgo I, Kirchdorfer AM. Comm 3 Notab Med 1982;12(9):721-727. Cited by:  Scaglione F et al., Evid Based Integrative Med 2005;2(4);195-206.  
  10. Forgo I. MMW 1983;125(38):822-824. Cited by:  Scaglione F et al., Evid Based Integrative Med 2005;2(4);195-206.
  11. Forgo I, Schimert G. Notab Med 1985;15(9):636-640. Cited by:  Scaglione F et al., Evid Based Integrative Med 2005;2(4);195-206.  
  12. Van Schepdael P. Acta Ther 1993;19:337-347. Cited by:  Scaglione F et al., Evid Based Integrative Med 2005;2(4);195-206.
  13. Kennedy DO, Scholey AB, Wesnes KA. Nutritional Neuroscience 2001;4:295-310.
  14. Scholey AB, Kennedy DO. Kennedy DO, Scholey AB, Wesnes KA. Physiol Behav. 2002;75(5):739-51.
  15. Hum Psychopharmacol 2002;17(1):35-44.
  16. Reay JL, Kennedy DO, Scholey AB. Journal of Psychopharmacology 2005 19(4):357-365.
  17. McKay, D. Alternative Medicine Review 2004; 9(1): 4-16. 
  18. Ardenne M von, Klemm W. Panminerva Med 1987 29(2): 143-150.
  19. Gross D, et al. Monaldi Arch Chest Dis 2002; 57: 5–6, 242–246.
  20. Scaglione F, et al. Drugs Exptl Clin Res 1990 (10); 537-542
  21. D Gross, et al. Schweiz Z für Ganzheits Medizin 1995;1/95:29:33.  Cited by:  Scaglione F et al., Evid Based Integrative Med 2005;2(4);195-206.
  22. Pannacci M, et al. Biochemistry and Pharmacology 2016; 5(5) open access.
  23. Scaglione et al. Drugs Exptl Clin Res 1996;22(2):65-72.

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