The history of Alpha-cyclodextrin use
Alpha-cyclodextrin’s fat binding effect was discovered nearly a decade ago by researchers at Wayne State University in America. Pre-clinical studies 2,3 identified that 1 gram of alpha-cyclodextrin is able to bind and eliminate up to 9 grams of dietary fat.
These trials paved the way for further research, including a preclinical study4 suggesting that alpha-cyclodextrin may have a greater binding affinity for saturated fats and trans fatty acids.
Key studies on FBCx
Over the last 10 years, research has established the supportive effects of FBCx on blood cholesterol and triglyceride level management within the normal range.
The most recent clinical studies on FBCx are:
- The Beneficial Effects α-Cyclodextrin on BloodLipids and Weight Loss in Healthy Humans Comerford KB, et al. Obesity 2011;19:1200-1204.
- The Effect of α-Cyclodextrin on postprandial lipid and glycemic responses to a fat-containing meal, Jarosz PA, et al. Metabolism 2013;62(10):1443-7 3.
How it works
When taken with a fatty meal or snack, FBCX (alpha-cyclodextrin) binds (attaches) to dietary fats (fats in foods consumed in the diet). This forms a complex which is then passed naturally through the bowel, helping to prevent the fat from being digested and absorbed.