Actaea Racemosa

What is Actaea racemosa?

Actaea racemosa, also known as Black cohosh, is a perennial herb native to North America. Extracts of Actaea racemosa are made from the root and underground stems (rhizomes) and then formulated into a product.

Actaea racemosa is found in Flordis’ Femular products.

The history of Actaea racemosa use

Historically, Actaea racemosa was used by North American Indians.  In the 19th century America, it gained popularity as a home remedy. Actaea racemosa also became a popular herbal remedy among European women in the 1950s.

Today, Actaea racemosa is widely used by women all around the world who are looking for a natural way to address hot flushes and other symptoms of menopause.

The specific extract used by Flordis

The specific Actaea racemosa extract used by Flordis is known as Ze 450. Ze 450 is cultivated, extracted and formulated using a specialised process. This individual and highly technical process helps ensure a consistent form and amount of Ze 450 is used in every formulation - meaning each final product will contain the same high quality active ingredient.

We believe it’s the science behind growing, harvesting and processing that delivers the true health benefits of natural medicines. The consistency of each batch of Flordis Femular and Femular Forte is underpinned by our commitment to tightly controlled growing methods, harvesting, and cultivating and using precise processes to produce consistent crops. This means that you can expect reliable outcomes when taking a Flordis medicine.

The Actaea racemosa extract used by Flordis, Ze 450, has been well researched and has demonstrated good results in clinical trials.

Key studies on Ze 450

Clinical trials have demonstrated the Ze 450 extract’s ability to relieve menopausal symptoms:

  • An observational study of 442 women suggested patients who took Ze 450 showed significant improvement of menopausal symptoms.1
  • A 12-week, randomised, double-blind, placebo-controlled, 3-armed trial of 180 menopausal women demonstrated that Ze 450 is effective and well-tolerated for relieving menopausal symptoms.2

How it works

Scientists still aren’t sure exactly how Actaea racemosa helps to relieve hot flushes and other menopausal symptoms. Some researchers have suggested it plays a role in serotonin and opioid systems as well as possibly other neurotransmitter systems. Research into Actaea racemosa’s specific mechanism of action is ongoing. Scientific studies suggest Ze 450 can effectively relieve the symptoms of menopause without having an oestrogenic like effect. 3,4

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1.Drewe J et al. Phytomedicine 2013; 20:659-666.  2.Schellenberg R et al. Evidence-Based Complementary and Alternative Medicine. 2012. doi: 10.1155/2012/260301.  3.Burdette JE et al. J Agric Food Chem 2003; 51(19): 5661-5670.  4.Rhyu M-R et al. Agric Food Chem. 2006; 54(26):9852-9857