Supports liver health

Based on 68 reviews

Is Legalon right for you? 

Is your liver under stress due to overindulgence - such as overconsumption of rich, fatty and processed foods?  

Are you feeling tired and fatigued? 

Does your liver need support recovering from toxic overload - such as overconsumption of alcohol?^

A healthy functioning liver is vital for good health but many of us put our liver under stress which may lead to feelings of fatigue, sluggishness, nausea and uncomfortable fullness. 

So if you’ve been overindulging or your liver needs a detox, Legalon may be an option for you. Legalon may help relieve fatigue due to a liver under stress. 

Legalon is scientifically researched in helping to protect, detoxify and regenerate liver cells*. Recommended for over 45 years Legalon may also help relieve gastrointestinal discomfort so you can feel the difference to your health.1

^Drink responsibly * Helps to protect liver cells against toxins and support regeneration of liver cells. Aids normal healthy detoxification and elimination processes in the body.

The Legalon Difference

Legalon is a natural medicine designed to support healthy liver function. This benchmark Milk thistle formulation has been used medically for over 45 years worldwide. Legalon is scientifically researched in helping to protect, detoxify and regenerate liver cells* by:

  • Having an antioxidant effect 2,3
  • Exhibiting an anti-inflammatory action2,4
  • Aiding the renewal of healthy liver cells2,4,5
  • Assisting normal healthy detoxification and elimination processes2,3

Further research shows Legalon can help relieve fatigue and mild gastrointestinal symptoms such as nausea and uncomfortable fullness.+ Legalon contains a specific extract of Silybum marianum (MZ 80), also known as Milk Thistle.

Learn more about Silybum marianum >



* Helps to protect liver cells against toxins and support regeneration of liver cells. Aids normal healthy detoxification and elimination processes in the body. +Legalon may help fatigue due to a liver under stress.

Product details


Legalon contains a specific extract of Silybum marianum (MZ 80), also known as Milk Thistle. This specific extract has demonstrated efficacy and tolerability in numerous clinical trials. Legalon is made in Germany using  patented manufacturing processes. Learn more about Legalon and the specific extract of Silybum marianum (MZ 80).


Available sizes

60 capsules  

Directions for use

Recommended dosage and directions

Adults: 1 capsule three times a day.

Once the desired therapeutic outcome is achieved, the dose may be reduced to 1 capsule twice daily for maintenance. Use for as long as liver support is needed.


Legalon capsules are well tolerated with no known drug interactions. Legalon has demonstrated positive results in a number of large-scale studies including one involving over 2000 participants with a very low incidence of side effects.1,6 Follow up tolerability data has shown that ongoing administration can be of continued benefit, following patients taking Legalon for up to six years.7


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Frequently asked questions

Is Legalon likely to have any side effects?

Legalon is generally well tolerated. In rare cases, a mild laxative action has been observed after taking Legalon. It is important to speak with a healthcare professional if you are concerned about possible side effects.

Does Legalon interact with any medications?

There are no known interactions between Legalon and other medications.  If you are concerned about taking Legalon with any prescription medications, it is important to speak with a healthcare professional.

Can Legalon be used in pregnancy and lactation?

Legalon is not recommended during pregnancy or lactation as there are no published studies to establish its safe use during pregnancy or while breastfeeding.

Does it matter if Legalon is taken before or after food?

Legalon can be taken on an empty stomach; this has the advantage of allowing the active agent, silymarin, to be more quickly absorbed into the body – therefore acting more rapidly and effectively. However, if you are experiencing any gastrointestinal problems, Legalon can be taken during or after meals.

How does Legalon differ from other silymarin products?

Legalon is clinically researched; it is the exact product that has been used in numerous clinical trials. This is very important for natural medicines as there can be great variance between products, even if they appear to use the same active ingredients, due to the plant that is used, growing methods, harvesting processes and manufacturing methods.

Is Legalon gluten free?

No gluten added. 

Does Legalon contain lactose?

No, Legalon does not contain lactose.

Will Legalon affect my ability to drive and use machines?

Legalon capsules have no known adverse effects in these situations.

Where can I find Legalon?

Legalon is available from naturopaths, herbalists, other natural health practitioners, selected health food stores and pharmacies. If you go to the Where to buy button above and follow the instructions, you will be able to find a list of practitioners, health food stores and pharmacies in your area that either stock Legalon or will know how to order Legalon. Even if your local pharmacy is not on the list, they will be able to order it in for you.


1. Albrecht M et al Z Klin Med (1992) 47 (2): 87-92. 2. World Health Organisation, 2002, WHOmonographs on selected medicinal plants Volume 2,World Health Organization, Geneva, Switzerland.3. Dehmlow C, et al. Hepatology. 1996;23:749-754. 4.Trappoliere M, et al. J. Hepatology. 2009; 50:1102-111.) 5. Velussi M, et al. J Hepatology. 1997; 26:871-879. 6. Saller R et al Drugs 2001; 61 (14): 2035-63 7. Ferenci et al. J Hepatology 1989; 9:105-113.