DONA Glucosamine Sulphate
Glucosamine Sulphate is a naturally occuring amino sugar necessary for the synthesis of connective tissue. Glucosamine is one of the building blocks of proteoglycans, the ground substance of articular cartilage which functions to attract water into the joint space for lubrication of the cartilage during movement.
DONA Glucosamine Sulphate works by maintaining joint health and lubricating and rebuilding cartilage that has been worn away by age progression or injury. In addition, it specifically reduces the structural degradation seen in the osteoarthritic joint.
Always read the label. Use only as directed. If symptoms persist patients should consult their healthcare professional.
Why take DONA Glucosamine?
DONA Glucosamine Sulphate is successfully used to help alleviate symptomatic osteoarthritis of the knee, hip, spine and hands. It acts on both the signs and symptoms, helps in the synthesis of new cartilage and reduces the breakdown of existing cartilage, thereby reducing inflammation. Treatment with DONA has been proven to improve joint mobility and relieve pain, as well as reduce swelling and tenderness. DONA has been shown to rebuild damaged cartilage, thus restoring articular function. DONA therefore nourishes the joint and without gut side effects common with synthetic medicine alternatives.
What is unique about DONA Glucosamine?
- DONA is the world's highest selling Glucosamine product
- The only brand proven effective with double-blind, placebo-controlled randomised clinical studies shown to assist in: promoting healthy cartilage; lubricating joints; supporting joint mobility and flexibility; protecting cartilage.
- DONA is also proven to reach the joints in humans, which is not proven with any other formulation of glucosamine.
- DONA has been developed and manufactured by ROTTAPHARM in Italy, world leader in Glucosamine products.
- In total, over twenty clinical trials have been conducted on DONA over the last ten years. In addition, a positive Cochrane Review was completed in 2000. In contrast studies on other formulations of glucosamine are inconclusive or have not been done at all.
- DONA Glucosamine Sulphate is a registered drug in Europe in recognition of the specific clinical evidence supporting its efficacy.
Lifestyle modifications for Osteoarthritis
Weight reduction lessens the burden placed on lower extremity joints such as hips and knees. Excess weight increases the load placed on these joints, which can speed up the breakdown of cartilage. A diet rich in whole foods which exert anti-inflammatory effects such as green leafy vegetables, fresh fruit, legumes, and cold water, oily fish containing Omega 3, as well as lean protein can all help to promote joint repair and pain reduction. Alternatively, there are many foods which can exacerbate joint degredation, inflammation and pain which should be avoided.
These include:
- Refined carbohydrates which negate effective insulin metabolism, leading to weight gain and the promotion of inflammation.
- Inadequate protein intake which limits tissue repair.
- Foods rich in Omega 6 fatty acids (sunflower, canola, soy, corn oil).
- Alcohol and processed, fast foods.
- Nightshade vegetables (potatoes, tomatoes, eggplant, capsicum, paprika).
Active ingredients per tablet
Each tablet contains:
Glucosamine Sulphate 750mg
Free of preservatives, artificial colours, artificial sweeteners, artificial flavours, gluten, yeast and dairy.
Dosage and considerations
Glucosamine Sulphate has been proven to be well tolerated in the gut, and assists in the management of osteoarthritis. The therapeutic dose is 1500mg per day, (two tablets of YourHealth DONA Glucosamine Sulphate taken once daily with food, or alternatively, one tablet taken twice daily). The therapeutic benefits of Glucosamine Sulphate can take between two and four weeks to take effect due to its mechanism of action, with optimal effects on joint mobility observed after 12 weeks of administration.
This product is not recommended for children, nor if you are pregnant, lactating, currently on medication or diabetic. Please consult your healthcare practitiner before taking it, particularly if you have an allergy to seafood. Use only as directed.
Clinical Evidence for the use of DONA Glucosamine Sulphate
Two 3-year long double-blind placebo-controlled, randomised studies have shown that the administration of DONA Glucosamine Sulphate slows disease progression in patients with knee osteoarthritis. According to the studies, patients who received the placebo experienced progressive joint space narrowing, representing further loss of cartilage. Those who received DONA Glucosamine Sulphate showed no further loss of cartilage on average, therefore reducing the progression of osteoarthritis. The studies also found that it is well tolerated in the gut.
Lancet.2001 Jan 27;357(9252):247-8
Arch.Intern.Med. 2002;162:2113-23
Where can I purchase DONA Glucosamine Sulphate
DONA is exclusively distributed in Australia and New Zealand by Flordis under distribution rights by Rottapharm.
DONA Glucosamine Sulphate can be purchased from health practitioners, selected pharmacies and health food stores.